一、基本信息:
高政,理学博士,硕士研究生导师。2021年毕业于山东农业大学,同年人才引进至BetWay·必威半导体股份有限公司,加入组织胚胎学教研室。联系方式:gaozheng@hbu.edu.cn。
二、研究方向:天然产物的分离纯化与生理药理活性
肠道稳态与机体健康
生殖发育与衰老退化
三、主持科研项目:
1、河北省自然科学基金青年基金项目:毛头鬼伞多糖高级结构表征及其降血糖效应的构效机制研究(C2022201038)。主持
2、河北省中医药管理局项目:菌物药树舌灵芝多糖类成分的分离纯化及抗肿瘤作用的构效机制(2022136)。主持
3、betway必威医学培育项目:毛头鬼伞多糖靶向GluT-1/NLRP3途径改善糖尿病炎症微环境的分子机制(2022B09)。主持
四、代表性论文:
(1) Gao, Z., Kong, D., Cai, W., Zhang, J. & Jia, L. (2020). Characterization and anti-diabetic nephropathic ability of mycelium polysaccharides from Coprinus comatus. Carbohydrate Polymers, 251, 117081.(中科院一区)
(2) Gao, Z., Liu, X., Wang, W., Yang, Q., Dong, Y., & Xu, N., et al. (2018). Characteristic anti-inflammatory and antioxidative effects of enzymatic- and acidic- hydrolysed mycelium polysaccharides by Oudemansiella radicata on LPS-induced lung injury. Carbohydrate Polymers, 204, 142-151.(中科院一区)
(3) Gao, Z., Zhang, C., Tian, C., Ren, Z., Song, X., & Wang, X., et al. (2018). Characterization, antioxidation, anti-inflammation and renoprotection effects of selenized mycelia polysaccharides from Oudemansiella radicata. Carbohydrate Polymers, 181, 1224-1234.(中科院一区)
(4) Gao, Z., Yuan, F., Li, H., Feng, Y., & Jia, L. (2019). The ameliorations of Ganoderma applanatum residue polysaccharides against CCl4 induced liver injury. International Journal of Biological Macromolecules, 137, 1130-1140. (中科院二区)
(5) Gao, Z., Zhang, C., Liu, H., Zhu, Y., Ren, Z., & Jing, H., et al. (2018). The characteristics and antioxidation of Oudemansiella radicata selenium polysaccharides on lipopolysaccharide-induced endo-toxemic mice. International Journal of Biological Macromolecules, 116,753-764. (中科院二区)
(6) Gao, Z., Li, J., Song, X., Zhang, J., Wang, X., & Jing, H., et al. (2017). Antioxidative, anti-inflammation and lung-protective effects of mycelia selenium polysaccharides from Oudemansiella radicata. International Journal of Biological Macromolecules, 104, 1158-1164.(中科院二区)
(7) Gao, Z., Lai, Q., Yang, Q., Xu, N., Liu, W., & Zhao, F., et al. (2018). The characteristic, antioxidative and multiple organ protective of acidic-extractable mycelium polysaccharides by Pleurotus eryngii var. tuoliensis on high-fat emulsion induced-hypertriglyceridemic mice. Scientific Reports, 8(1) 17500. (中科院三区)
(8) Xu, N., Gao, Z., Zhang, J., Jing, H., Li, S., & Ren, Z., et al. (2017). Hepatoprotection of enzymatic-extractable mycelia zinc polysaccharides by Pleurotus eryngii var. tuoliensis. Carbohydrate Polymers, 157, 196-206.(中科院一区)